Fruit, vegetables, and colorectal cancer risk: the European Prospective Investigation into Cancer and Nutrition

Description
We examined the relation between self-reported usual consumption of fruit and vegetables and the incidence of CRC. In the European Prospective Investigation into Cancer and Nutrition (EPIC), 452,755 subjects (131,985 men and 320,770 women) completed a dietary questionnaire in 1992–2000 and were followed up for cancer incidence and mortality until 2006. A multivariate Cox proportional hazard model was used to estimate adjusted hazard ratios (HRs) and 95% CIs. These findings suggest that a high consumption of fruit and vegetables is associated with a reduced risk of CRC, especially of colon cancer. This effect may depend on smoking status. Am J Clin Nutr 89: 1441-1452, 2009.
URL
http://www.ajcn.org/cgi/content/abstract/89/5/1441

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